Friday, January 31, 2020

Critically discuss issues with determining recommendations for vitamin Essay

Critically discuss issues with determining recommendations for vitamin D intake - Essay Example The proceeding process is their hydroxylation to form 25-hydroxyvitamin. The total of 25-hydroxyvitamin D2 together with 25-hydroxyvitamin D3 levels in serum is used as an indicator of vitamin D nutritional status. Studies indicate that this level increases following exposure to sunlight, or dietary intake of vitamin D (Rajakumar et al., 2014). 25-hydroxyvitamin D is hydroxylated to 1,25-dihydroxyvitamin D (calcitriol) in the kidney, a reaction catalyzed by 25-hydroxyvitamin D-1alpha-hydroxylase. Regulation of this reaction is by serum phosphorus, calcium, parathyroid hormone (PTH), fibroblast growth factor 23 and 1,25-dihydroxyvitamin. 1,25-dihydroxyvitamin D production has also been demonstrated in the skin, parathyroid gland, breast, colon, prostate, and immune system and bone cells. 1,25-dihydroxyvitamin D then binds to a receptor of vitamin D in the nucleus of a cell and recruits retinoic acid X receptor. This VDR/RXR complex binds small sequences of DNA called vitamin D response elements (VDREs) (Battault et al., 2013). It then initiates a cascade of molecular interactions that modulate the transcription of specific genes. Vitamin D regulates calcium and phosphorus homeostasis that are necessary for the maintenance of bone mineralization (Vieth, 2012). In the endocrine system Vitamin D regulates insulin secretion. Investigation shows that it is a potent immune system modulator. It also exhibits effects in the cardiovascular system regulating blood pressure. Severe vitamin D deficiency results in a condition known as rickets in children and osteomalacia in adults since it is important for development and maintenance of the bone structure (Persson et al., 2013). Osteoporosis has been linked to secondary hyperthyroidism caused by vitamin D deficiency. Increased PTH secretion by the parathyroid glands result in increased bone resorption increasing the bone breakdown and precipitate osteoporosis. Cancer,

Thursday, January 23, 2020

How Are Suspense and Tension Created in The Red Room? Essay -- English

How Are Suspense and Tension Created in The Red Room? In The Red Room by H.G. Wells a lot of suspense and tension is created. The Red Room fits into the gothic genre because it has some of the requirements for a gothic story in it, like, being set in a castle, an atmosphere of mystery and suspense, a prophecy, the supernatural and high levels of emotion. The story creates tension in lots of ways such as, shadows, noises, charcters and general mystery surrounding the red room. At the beginning of The Red Room the author creates tension by having the narrator straight away in a scene which is unusual to him, he is in a dark old room with old people who are mostly disfigured and slightly other worldly in the way they look and behave. â€Å"†¦ I had scarce expected these grotesque custodians.† He sees them not as ordinary people but as being grotesque so is clearly unhappy being with them. The author also immediately creates tension by talking of ghosts and the supernatural straightaway. â€Å"†¦ It will take a very tangible ghost to frighten me.† So we already have talk of ghosts in only the first line! As the narrator begins his journey to the red room more tension is created. â€Å"†¦ and my candle flared and made the shadows cower a quiver, the echoes rang up and down the spiral staircase†¦Ã¢â‚¬  so we have shadows cowering and quivering which is exactly what people do when they are frightend, the shadows are also being personified which could be a representation of the narrator’s fear. The author uses shadows again to create tension when he is on his way to the red room. â€Å"†¦ and as a shadow came sweeping up after me†¦Ã¢â‚¬  so we feel that the narrator is being chased up the staircase by something perhaps not of this worl... ...king him and this could result in something happening to him. The description also enables him to understand how the rumours in the red room could have started which makes him very nervous. Light and dark are obviously very symbolic, dark represents danger and the unknown whereas light means we are safe because we can see everything around us and it is harder to be fooled by noises or shadows in the light. Tension and suspense were constantly created in The Red Room by H.G. Well’s using various techniques, the writer uses a lot of different techniques to keep the reader wondering and to make sure that tension and suspense are always present in the story. In my opinion there is no one technique which is used to greater effect than any other one. I think that they are all used in equally effective amounts and they all help to create suspense and tension.

Wednesday, January 15, 2020

Fast food restaurant Essay

All such food is categorized as fast food which can be prepared and served quickly. Restaurants and kiosks provide fast food with precooked or preheated ingredients and usually served at a packaged form (Pollan, 2009). In the beginning, American hamburger and fries was considered as the traditional fast food but now the field has been widely diversified and food like pizzas, fish and chips, burgers from McDonalds and Kentucky Fried Chicken etc. are all considered fast food. Fast food market has shown an enormous and steady growth. In 2006 alone the market has reached to $102. 4 billion with an annual growth rate of 4. 8% (Adams, 2007). Fast food chains like McDonalds operate in more than 126 countries in six continents having more than 31,000 restaurants globally (Arndt, 2007). Burger King, another worldwide fast food chain, has operations in more than 65 countries of the world; KFC restaurants located over 25 countries, Subways is present in 90 countries with total 39,129 restaurants and so and so forth (Buthrie, Lin & Frazao, 2002). However, according to most of researches, fast food is not at all fit for health and can cause serious problems. According to Marion Nestle, Chair of New York University’s Department of Nutrition, Food Studies, and Public Health, â€Å"the increased calories in American diets come from eating more food in general, but especially more of foods high in fat (meat, dairy, fried foods, grain dishes with added fat), sugar (soft drinks, juice drinks, desserts), and salt (snack foods)† (Nestle, 2002; p. 10). This report discusses some positive as well as negative points of taking fast food. Reasons for popularity Before delving into the positive and negative aspects of fast food, it seems appropriate if we discuss the reasons of fast food popularity. The question is what compels the Americans to eat such poorly balanced food? The answer of the question is not simple and involves many factors. First of all, every culture has its own values, philosophies, and the way to react to the things occurring in their lives. These reactions depend upon the culture they belong too. In present family structure and busy life it has been observed that the increasing communication deficit between parents and children has created a gulf between parents and children. This changed life style, especially in low-income and single-parent families, has compelled the children to take unhealthy and junk food more often than required (Ritzer, 2000). Advertising also played a major role in increasing the fast food popularity in America. According to National Cancer Institute, â€Å"Commercial advertisers have learned that a consistent and prominent presence in the marketplace is key to achieving and holding market share† (National Cancer Institute, 2000). Statistics revealed that in 2004 the total expenditure of different food items including fast food restaurants was approximately $11. 26 billion. Fast food advertisers target ethnic minorities directly through their own media outlets and programs. Food items which are advertised for ethnic minorities are usually unbalanced and unhealthy as compared to the food advertised for general audience (Reyes, 2005). Research conducted in 2005 depicted that more than 52 percent of food items advertisement published in Hispanic fashion and social magazines were advertised unhealthy and unbalanced food as compared to 29 percent such advertisements published in general magazines (Duerksen et.al. , 2005). Fast food items advertising usually target children in order to create and establish brand loyalty at an early age (Wiecha et al. , 2006). Among the six brands which have enjoyed very strong recognition in children, four are related to food, i. e. Cheerios, McDonald’s, Pop-Tarts, and Coke (Comiteau, 2003). These companies relied on the fact that the children would emotionally connected to these companies even in their adulthood (Comiteau, 2003). Nevertheless, recent research shows that consumers prefer to buy fast food from supermarkets. Because they have the perception that supermarkets provide healthier food options ( Advertising and marketing very significantly influence the buying behavior of people and the notion cannot be rejected in totality that frequent use of this unhealthy food is a major cause of increasing obesity. According to a study, television advertisements and television viewing is directly associated with popularity of junk food (Bowman et al. , 2004). Advantages of using fast food The basic and most obvious advantage of fast food is its cost and speed. Fast food is very easy and quick to prepare and serve. As discussed above, the number of single parent household is continuously increasing in United States. Such single parents not only have to work to earn a respectable living but also have to prepare food for the family. For such persons fast food is an easy and cost effective solution. Fast food not only prepared at home easily but can also be ordered from fast food restaurants which usually have special offers and deals available to make it cheaper or more cost effective. Fast food comprises and enjoys the biggest chunk of food industry. It has, in United States alone, sale of $120 billion with the help of more than 200,000 restaurants. Fast food industry has been very successful in term of operation expansion by utilizing international franchising. The administration of different fast food companies have learned by the passage of time how to make the most of the sales potential of a fast food franchise by practically adopting an idea by giving it a functional methodology. This is one main cause why fast food franchises have been a symbol of success among the contemporary food businesses. Fast food industry gives minimal wages and financial benefits to their workers (McDonald’s Australia); nevertheless, it provides jobs to approximately 3. 5 million people.

Tuesday, January 7, 2020

Essay on Three Branches of Government - 725 Words

Week 3 Assignment 1 ------------------------------------------------- Top of Form Bottom of Form If you are using the Blackboard Mobile Learn App, please click View in Browser. Click the link above to submit your assignment. Students, please view the Submit a Clickable Rubric Assignment in the Student Center. Instructors, training on how to grade is within the Instructor Center. Assignment 1 Branches of Government Create a flowchart of the three branches of government and associate two (2) Uniform Commercial Code (UCC) clauses for each branch of government. Designate the relationships among the governmental branches. In an accompanying document, exemplify the types of powers of each branch of government and include†¦show more content†¦* Given a business situation, evaluate the various options for resolving a business dispute from a legal perspective and develop an optimal course of action to resolve the dispute. * Use technology and information resources to research issues in commercial law. * Write clearly and concisely about commercial law using proper writing mechanics. Grading for this assignment will be based on answer quality, logic / organization of the paper, and language and writing skills, using the following rubric. Please click here to view the grading rubric. The assignment will be graded using the following rubric: Points: 150 | Assignment 1: Branches of Government | Criteria | UnacceptableBelow 70% F | Fair70-79% C | Proficient80-89% B | Exemplary90-100% A | 1. Organize all three (3) branches of government in a flowchart format.Weight: 25% | Did not submit or incompletely organized all three (3) branches of government in a flowchart format. | Partially organized all three (3) branches of government in a flowchart format. | Satisfactorily organized all three (3) branches of government in a flowchart format. | Thoroughly organized all three (3) branches of government in a flowchart format. | 2. Designate two (2) UCC clauses that align with each branch.Weight: 25% | Did not submit or incompletely designated two (2) UCC clauses that align with each branch. | Partially designated two (2) UCC clauses that align with eachShow MoreRelatedThree Branches of Government1117 Words   |  5 PagesThree Branches of the Federal Government In May 1787, 55 delegates from 12 states, Rhode Island declined, met in Philadelphia for the Constitutional Convention. 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